Article
Chromosome aberrations in Raynaud's phenomenon.
European journal of dermatology : EJD - 1 Jan 2000
Porciello Giovanni, Scarpato Roberto, Storino Franca, Migliore Lucia, Ferri Clodoveo, Cagetti Francesca, Morozzi Gabriella, Bellisai Francesca, Marcolongo Roberto, Galeazzi Mauro
Abstract excerpt
We evaluated the occurrence of spontaneous chromosome damage in cultured peripheral lymphocytes of subjects with idiopathic and pre-scleroderma Raynaud's phenomenon, by means of molecular cytogenetic analysis. Using the micronucleus assay as a marker of chromosome alteration, we studied 30 patients with pre-scleroderma Raynaud's phenomenon, 30 patients with idiopathic Raynaud's phenomenon and 30 healthy subjects....
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