Article
Cytogenetic abnormalities in PHA-stimulated lymphocytes from patients with Langerhans cell histiocytosis
1 Oct 2000
Abstract excerpt
The aetiopathogenesis of Langerhans cell histiocytosis (LCH) is still undefined. Constitutional abnormalities in LCH have rarely been reported. One study showed chromosomal instability in lesional cells from three patients. No chromosomal studies are available on peripheral blood lymphocytes. Peripheral blood lymphocytes were analysed for the presence of chromatid and/or chromosomal breaks and structural...
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