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Article

Genomic instability in scleroderma.

Asian Pacific journal of allergy and immunology - 1 Jan 2000

Roberts-Thomson P J, Male D A, Walker J G, Cox S R, Shen X, Smith M D, Ahern M J, Turner D R

Abstract excerpt

Scleroderma is an enigmatic rheumatic disorder of uncertain etio-pathogenesis. Cancer has an approximately two-fold higher incidence in scleroderma patients than in the general population. There are preliminary data of acquired genetic damage in scleroderma but the significance of these observations are uncertain. To determine somatic mutation frequency at the glycophorin-A (GPA) locus in patients with limited...

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PMID: 15565952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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