Article
[Correlation of expression of RhoA (RhoC and their effector ROCK-1 with malignant phenotype of ovarian cancer cells in vitro].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 2004
Han Zhi-qiang, Zhang A-li, Wu Ming-fu, Liu Yu-lan, Chen Gang, Li Fu-jun, Gao Qing-lei, Liao Guo-ning, Lu Yun-ping, Wang Shi-xuan, Ma Ding
Abstract excerpt
OBJECTIVE: To investigate the expression of RhoA, RhoC and their effector ROCK-1 in four ovarian cancer cell lines in vitro and their correlation with invasiveness. METHODS: Expression of RhoA, RhoC and ROCK-1 mRNA and protein in four ovarian cancer cell lines SW626, Skov-3, A2780 and Caov-3 was detected by RT-PCR and Western blot assay. Invasion assay was done in Boyden chamber. RESULTS: The expression levels of...
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