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Article

Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily.

The Journal of experimental medicine - 6 Sept 2004

Moir Susan, Malaspina Angela, Pickeral Oxana K, Donoghue Eileen T, Vasquez Joshua, Miller Natalie J, Krishnan Surekha R, Planta Marie A, Turney John F, Justement J Shawn, Kottilil Shyamasundaran, Dybul Mark, Mican JoAnn M, Kovacs Colin, Chun Tae-Wook, Birse Charles E, Fauci Anthony S

Abstract excerpt

Human immunodeficiency virus (HIV) infection leads to numerous perturbations of B cells through mechanisms that remain elusive. We performed DNA microarray, phenotypic, and functional analyses in an effort to elucidate mechanisms of B cell perturbation associated with ongoing HIV replication. 42 genes were up-regulated in B cells of HIV-viremic patients when compared with HIV-aviremic and HIV-negative patients,...

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Identifiers

PMID: 15353552
DOI: 10.1084/jem.20032236
PMCID: PMC2262955

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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