Activation of human cyclin-dependent kinases in vitro.

doi:10.1091/mbc.3.5.571

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Article

Activation of human cyclin-dependent kinases in vitro.

Molecular biology of the cell - 1 May 1992

Desai D, Gu Y, Morgan D O

Abstract excerpt

We have analyzed the activation of human cyclin-dependent kinases in a cell-free system. Human CDC2, cyclin-dependent kinase 2 (CDK2), cyclin A, and cyclin B1 were produced in insect cells by infection with recombinant baculoviruses. CDC2 or CDK2 monomers in lysates of infected cells could be act...

Topics

Amino Acid Sequence
Base Sequence
CDC2 Protein Kinase
CDC2-CDC28 Kinases
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinases
Cyclins
Enzyme Activation
Humans
In Vitro Techniques
Molecular Sequence Data
Mutation
Phosphorylation
Protein Kinases
Protein Serine-Threonine Kinases

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