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Article

Factor XIII Val34Leu polymorphism modulates the prothrombotic and inflammatory state associated with atrial fibrillation.

Journal of molecular and cellular cardiology - 1 Sept 2004

Marín Francisco, Corral Javier, Roldán Vanessa, González-Conejero Rocío, del Rey María Luz, Sogorb Francisco, Lip Gregory Y H, Vicente Vicente

Abstract excerpt

UNLABELLED: Atrial fibrillation (AF) has been shown to confer a prothrombotic or hypercoagulable state, which could be related to inflammation. Factor XIII (FXIII) catalyses the cross-linking of fibrin monomers, increasing clot resistance; specifically, a common polymorphism, Val34Leu, in the FXIII-A subunit gene has been associated with more rapid FXIII activation. We hypothesised a role for this polymorphism in...

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Identifiers

PMID: 15350843
DOI: 10.1016/j.yjmcc.2004.06.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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