Article
Correlation between rules-based interpretation and virtual phenotype interpretation of HIV-1 genotypes for predicting drug resistance in HIV-infected individuals.
Journal of virological methods - 1 Oct 2004
Gallego Oscar, Martin-Carbonero Luz, Aguero Jesus, de Mendoza Carmen, Corral Angelica, Soriano Vincent
Abstract excerpt
Drug resistance testing provides useful information for managing HIV-infected patients. Phenotyping could add complementary information to genotyping and occasionally be more useful, although is less available to clinicians. Large paired geno-pheno databases have allowed the prediction of phenotypes from genotypes. However, the accuracy of these virtual phenotypes (vPT) in a clinical setting has not been well...
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