Article
HIV susceptibility to amprenavir: phenotype-based versus rules-based interpretations.
The Journal of antimicrobial chemotherapy - 1 Nov 2003
Scudeller Luigia, Torti Carlo, Quiros-Roldan Eugenia, Patroni Andrea, Lo Caputo Sergio, Moretti Francesca, Mazzotta Francesco, Donati Elisa, Vivarelli Angela, Carosi Giampiero
Abstract excerpt
OBJECTIVES: The objective was to study genotypic correlates of discordant interpretations of amprenavir (APV) resistance between a rules-based algorithm and either recombinant phenotype or virtual phenotype. METHODS: HIV resistance mutations found in patients from the GenPheRex study were interpreted with VGI-TRUGENE (version 5.0; VGI) and compared with either recombinant-phenotype (Antivirogram, r-PHT) or...
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