Article
Genotyping of AR and PSA polymorphisms in a patient with Klinefelter syndrome, non-Hodgkin lymphoma, and adenocarcinoma of the prostate.
Cancer genetics and cytogenetics - 1 Sept 2004
Mattos Dos Santos Rodrigo, Aparecida Rainho Claudia, Carlos Souza Trindade José, Carlos Souza Trindade Filho José, Lauro Viana De Camargo João, Regina Rogatto Silvia
Abstract excerpt
It has been hypothesized that the AR (androgen receptor) gene binds the two PSA (prostate-specific antigen) alleles with differing affinities and may differentially influence prostate cancer risk. In this article, we report a case of adenocarcinoma of the prostate in a 56-year-old man with Klinefelter syndrome (47,XXY) and non-Hodgkin lymphoma, as well as the AR and PSA genotype. AR and PSA gene polymorphisms...
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