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Article

Genomics and phenotypic profiles in dementia: implications for pharmacological treatment.

Methods and findings in experimental and clinical pharmacology - 1 Jan 2000

Cacabelos R, Fernández-Novoa L, Corzo L, Pichel V, Lombardi V, Kubota Y

Abstract excerpt

Constitutive genomics are probably determinant for the onset of dementia in conjunction with cerebrovascular and environmental factors. Furthermore, pharmacogenomic studies predict that the therapeutic response in Alzheimer's disease (AD) is genotype-specific, and that the expression of genes involved in the regulation of drug metabolism can influence efficacy and safety issues in pharmacotherapy. AD and dementia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15349138

Genes

APOE
ACE
AGT
APP
GPT
MAPT
PRNP

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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