Article
Genomic characterization of Alzheimer's disease and genotype-related phenotypic analysis of biological markers in dementia.
Pharmacogenomics - 1 Dec 2004
Cacabelos Ramón
Abstract excerpt
More than 180 genes distributed across the human genome are potentially involved in the pathogenesis of Alzheimer's disease (AD). The AD population shows a higher genetic variation rate than the control population. Significant differences in allelic distribution and frequency exist when AD-related polygenic clusters are compared with other forms of dementia, indicating that the genetic component in...
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