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Article

Pharmacogenomics in Alzheimer's disease.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Cacabelos Ramón

Abstract excerpt

Pharmacological treatment in Alzheimer's disease (AD) accounts for 10-20% of direct costs, and fewer than 20% of AD patients are moderate responders to conventional drugs (donepezil, rivastigmine, galantamine, memantine), with doubtful cost-effectiveness. Both AD pathogenesis and drug metabolism are genetically regulated complex traits in which hundreds of genes cooperatively participate. Structural genomics...

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Identifiers

PMID: 18370236
DOI: 10.1007/978-1-59745-205-2_10

Genes

APOE
ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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