Article
The application of functional genomics to Alzheimer's disease.
Pharmacogenomics - 1 Sept 2003
Cacabelos Ramón
Abstract excerpt
Alzheimer's disease (AD) is a polygenic/complex disorder in which more than 50 genetic loci are involved. Primary and secondary loci are potentially responsible for the phenotypic expression of the disease under the influence of both environmental factors and epigenetic phenomena. The construction of haplotypes as genomic clusters integrating the different genotype combinations of AD-related genes is a suitable...
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