Genetics of Alzheimer's disease. A rapidly evolving field.

Abstract excerpt

Genetic factors have a variable impact on Alzheimer's Disease (AD), ranging from familial forms that are transmitted in an autosomal dominant fashion to sporadic AD, where a polygenic component is present. Most genes conferring susceptibility to AD are related to amyloid-beta deposition (APP; PS1; PS2; APOE; Cystatin-C; ubiquilin-1), oxidative stress (NOS2; NOS3) and inflammatory response (IL-1 alpha; IL-1 beta;...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Interleukin-6
• Share to Amyloid beta-Peptides
• Share to Amyloid Precursor Protein Secretases