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Article

Characterization of two transgene insertional mutations at pirouette, a mouse deafness locus.

Audiology & neuro-otology - 1 Jan 2000

Odeh Hana, Hagiwara Nobuko, Skynner Michael, Mitchem Kristina L, Beyer Lisa A, Allen Nicholas D, Brilliant Murray H, Lebart M C, Dolan David F, Raphael Yehoash, Kohrman David C

Abstract excerpt

The mouse mutant 'pirouette' (pi) exhibits profound hearing loss and vestibular defects due to inheritance of a recessive mutation on chromosome 5. Dysfunction has been correlated with defects during maturation of sensory cells in the inner ear. As an initial step in characterizing pirouette at the genetic level, we have localized the candidate interval to a small region on central chromosome 5 by analysis of a...

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PMID: 15347914
DOI: 10.1159/000080701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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