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Article

Augmentation of leptin and hypoxia-inducible factor 1α mRNAs in the pre-eclamptic placenta

1 May 2004

Abstract excerpt

The placenta is a major source of leptin in the fetomaternal circulation, although its physiological role remains to be clarified. Leptin in the fetomaternal circulation is proposed to be a marker of acute stress in the fetus, and the fetus suffering from pre-eclampsia would be under chronic stress. In 16 pre-eclamptic placentas, the expressions of leptin, hypoxia-inducible factor 1alpha (HIF1alpha) and leptin...

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PMID: 15346662
DOI: 10.1080/0951359042000196277

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