Human umbilical cord and fetal membranes co-express leptin and its receptor genes

Abstract excerpt

Leptin, protein product of the ob gene, not only regulates food intake and energy expenditure but also has a number of other actions in the body. Leptin actions are mediated by its receptors that have either a long or a truncated intracellular domain, which is coupled to signal transduction pathways. Previous studies have demonstrated that human placenta expresses both leptin and its receptors. However, it is not...

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