Effects of the ApoE epsilon4 allele on olfactory function in Down syndrome.

doi:10.3233/jad-2004-6407

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Article

Effects of the ApoE epsilon4 allele on olfactory function in Down syndrome.

Journal of Alzheimer's disease : JAD - 1 Aug 2004

Sliger Melissa, Lander Timothy, Murphy Claire

Abstract excerpt

The present study investigated the effects of the apolipoprotein E (ApoE) epsilon4 allele, a risk factor for Alzheimer's disease (AD), on olfactory function in Down syndrome (DS). Brain areas critical to olfactory processing, particularly the entorhinal cortex, show the earliest neuropathological...

Topics

Adolescent
Adult
Alleles
Alzheimer Disease
Apolipoproteins E
Brain
Down Syndrome
Female
Humans
Male
Middle Aged
Olfaction Disorders

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