Article
Endothelin induces differentiation of ANP-EGFP expressing embryonic stem cells towards a pacemaker phenotype.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2004
Gassanov Natig, Er Fikret, Zagidullin Naufal, Hoppe Uta C
Abstract excerpt
Currently, only limited insight into mechanisms promoting the differentiation and specification of the mammalian cardiac conduction system is available. Therefore, we established a murine embryonic stem (ES) cell line stably expressing the enhanced green fluorescent protein (EGFP) under the transcriptional control of the human atrial natriuretic peptide (ANP) promoter to further characterize the development of...
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