Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types.

Mechanisms of development - 1 Nov 1993

Maltsev V A, Rohwedel J, Hescheler J, Wobus A M

Abstract excerpt

Pluripotent embryonic stem cells (ESC, ES cells) of line D3 were differentiated in vitro and via embryo-like aggregates (embryoid bodies) of defined cell number into spontaneously beating cardiomyocytes. By using RT-PCR technique, alpha- and beta-cardiac myosin heavy chain (MHC) genes were found to be expressed in embryoid bodies of early to terminal differentiation stages. The exclusive expression of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cells, Cultured
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Myocardium

Share to Phenotype

Share to Stem Cells

Source

Identifiers

PMID: 8155574
DOI: 10.1016/0925-4773(93)90015-p

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types.PMID 8155574Read ↗

Embryonic stem cells and cardiomyocyte differentiation: phenotypic and molecular analyses.Semantic proximity Read ↗

Differentiation of pluripotent embryonic stem cells into cardiomyocytes.Semantic proximity Read ↗

Developmental Changes in Cardiomyocytes Differentiated from Human Embryonic Stem Cells: A Molecular and Electrophysiological ApproachSemantic proximity Read ↗

Non-Cardiomyocytes Influence the Electrophysiological Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes During DifferentiationSemantic proximity Read ↗

Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem CellsSemantic proximity Read ↗

Early cardiac development: a view from stem cells to embryos.Semantic proximity Read ↗

Molecular analysis of cardiomyocytes derived from human embryonic stem cellsSemantic proximity Read ↗

Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype.Semantic proximity Read ↗

Differentiation Pathways in Human Embryonic Stem Cell‐Derived CardiomyocytesSemantic proximity Read ↗

Differentiation of Human Embryonic Stem Cells to CardiomyocytesSemantic proximity Read ↗

Stem cell-derived cardiomyocytes demonstrate arrhythmic potential.Semantic proximity Read ↗

Endothelin induces differentiation of ANP-EGFP expressing embryonic stem cells towards a pacemaker phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.