Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells.

Journal of cardiovascular translational research - 1 Dec 2013

Chan Yau-Chi, Ting Sherwin, Lee Yee-Ki, Ng Kwong-Man, Zhang Jiao, Chen Zi, Siu Chung-Wah, Oh Steve K W, Tse Hung-Fat

Abstract excerpt

While human embryonic stem cells (hESCs) can differentiate into functional cardiomyocytes, their immature phenotypes limit their therapeutic application for myocardial regeneration. We sought to determine whether electrical stimulation could enhance the differentiation and maturation of hESC-derived cardiomyocytes. Cardiac differentiation was induced in a HES3 hESC line via embryoid bodies formation treated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium Signaling
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electric Stimulation

Share to Embryonic Stem Cells

Share to Membrane Potentials

Share to Myocytes, Cardiac

Share to p38 Mitogen-Activated Protein Kinases

Share to Protein Kinase Inhibitors

Source

Identifiers

PMID: 24081385
DOI: 10.1007/s12265-013-9510-z

Genes

GATA4
HCN1
HES3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells.PMID 24081385Read ↗

Differentiation of Human Embryonic Stem Cells to CardiomyocytesSemantic proximity Read ↗

Dynamic Electrical Stimulation Promotes hiPSC-CM Differentiation and FunctionalitySemantic proximity Read ↗

Non-Cardiomyocytes Influence the Electrophysiological Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes During DifferentiationSemantic proximity Read ↗

Structural and Functional Maturation of Cardiomyocytes Derived from Human Pluripotent Stem CellsSemantic proximity Read ↗

Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes.Semantic proximity Read ↗

Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived CardiomyocytesSemantic proximity Read ↗

Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype.Semantic proximity Read ↗

Developmental Changes in Cardiomyocytes Differentiated from Human Embryonic Stem Cells: A Molecular and Electrophysiological ApproachSemantic proximity Read ↗

Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac MyocytesSemantic proximity Read ↗

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes.Semantic proximity Read ↗

Molecular and Functional Evidence of HCN4 and Caveolin-3 Interaction During Cardiomyocyte Differentiation from Human Embryonic Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.