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Article

Impaired repression at a vasopressin promoter polymorphism underlies overexpression of vasopressin in a rat model of trait anxiety.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 2004

Murgatroyd Chris, Wigger Alexandra, Frank Elisabeth, Singewald Nicolas, Bunck Mirjam, Holsboer Florian, Landgraf Rainer, Spengler Dietmar

Abstract excerpt

Two inbred rat lines have been developed that show either high (HAB) or low (LAB) anxiety-related behavior. The behavioral phenotype correlates with arginine vasopressin (AVP) expression at the level of the hypothalamic paraventricular nucleus (PVN), but not supraoptic nucleus, with HAB animals overexpressing the neuropeptide in both magnocellular and parvocellular subdivisions of the PVN. We detected a number of...

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Identifiers

PMID: 15342744
DOI: 10.1523/JNEUROSCI.1614-04.2004
PMCID: PMC6729621

Genes

AVP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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