Article
QTL mapping for traits associated with stress neuroendocrine reactivity in rats.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jul 2005
Llamas Bastien, Contesse Vincent, Guyonnet-Duperat Véronique, Vaudry Hubert, Mormède Pierre, Moisan Marie-Pierre
Abstract excerpt
In the present study we searched for quantitative trait loci (QTLs) that affect neuroendocrine stress responses in a 20-min restraint stress paradigm using Brown-Norway (BN) and Wistar-Kyoto-Hyperactive (WKHA) rats. These strains differed in their hypothalamic-pituitary-adrenal axis (plasma ACTH and corticosterone levels, thymus, and adrenal weights) and in their renin-angiotensin-aldosterone system reactivity...
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