Article
Vasopressin deletion is associated with sex-specific shifts in the gut microbiome.
Gut microbes - 2 Jan 2018
Fields Christopher T, Chassaing Benoit, Paul Matthew J, Gewirtz Andrew T, de Vries Geert J
Abstract excerpt
Brattleboro rats harbor a spontaneous deletion of the arginine-vasopressin (Avp) gene. In addition to diabetes insipidus, these rats exhibit low levels of anxiety and depressive behaviors. Recent work on the gut-brain axis has revealed that gut microbiota can influence anxiety behaviors. Therefore, we studied the effects of Avp gene deletion on gut microbiota. Since Avp gene expression is sexually different, we...
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