Article
Regulation of the intracellular free iron pool by Dpr provides oxygen tolerance to Streptococcus mutans.
Journal of bacteriology - 1 Sept 2004
Yamamoto Yuji, Fukui Kôichi, Koujin Naoko, Ohya Hiroaki, Kimura Kazuhiko, Kamio Yoshiyuki
Abstract excerpt
Dpr is an iron-binding protein required for oxygen tolerance in Streptococcus mutans. We previously proposed that Dpr could confer oxygen tolerance to the bacterium by sequestering intracellular free iron ions that catalyze generation of highly toxic radicals (Y. Yamamoto, M. Higuchi, L. B. Poole, and Y. Kamio, J. Bacteriol. 182:3740-3747, 2000; Y. Yamamoto, L. B. Poole, R. R. Hantgan, and Y. Kamio, J. Bacteriol....
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