Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibiting the BfrB:Bfd interaction in Pseudomonas aeruginosa causes irreversible iron accumulation in bacterioferritin and iron deficiency in the bacterial cytosol.

Metallomics : integrated biometal science - 21 Jun 2017

Eshelman Kate, Yao Huili, Punchi Hewage Achala N D, Deay Jacqueline J, Chandler Josephine R, Rivera Mario

Abstract excerpt

Iron is an essential nutrient for bacteria but the reactivity of Fe2+ and the insolubility of Fe3+ present significant challenges to bacterial cells. Iron storage proteins contribute to ameliorating these challenges by oxidizing Fe2+ using O2 and H2O2 as electron acceptors, and by compartmentalizing Fe3+. Two types of iron-storage proteins coexist in bacteria, the ferritins (Ftn) and the heme-containing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome b Group
Share to Cytosol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ferredoxins

Share to Ferritins

Share to Homeostasis

Share to Protein Interaction Domains and Motifs

Share to Pseudomonas aeruginosa

Source

Open in PubMed Open full text

Identifiers

PMID: 28318006
DOI: 10.1039/c7mt00042a
PMCID: PMC5494978

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibiting the BfrB:Bfd interaction in Pseudomonas aeruginosa causes irreversible iron accumulation in bacterioferritin and iron deficiency in the bacterial cytosol.PMID 28318006Read ↗

Ferroptosis and iron-based therapies in Pseudomonas aeruginosa infections: From pathogenesis to treatmentSemantic proximity Read ↗

Regulation of Pseudomonas aeruginosa Virulence by Distinct Iron SourcesSemantic proximity Read ↗

Ferritin mutants of Escherichia coli are iron deficient and growth impaired, and fur mutants are iron deficient.Semantic proximity Read ↗

Ins and Outs: Recent Advancements in Membrane Protein-Mediated Prokaryotic Ferrous Iron TransportSemantic proximity Read ↗

Iron sequestration by human lactoferrin stimulates P. aeruginosa surface motility and blocks biofilm formationSemantic proximity Read ↗

Iron Acquisition Strategies of Bacterial PathogensSemantic proximity Read ↗

Role and regulation of heme iron acquisition in gram-negative pathogensSemantic proximity Read ↗

Ferritin and ferrihydrite nanoparticles as iron sources for Pseudomonas aeruginosa.Semantic proximity Read ↗

Ferritin from the obligate anaerobe Porphyromonas gingivalis: purification, gene cloning and mutant studies.Semantic proximity Read ↗

Interplay between iron homeostasis and virulence: Fur and RyhB as major regulators of bacterial pathogenicity.Semantic proximity Read ↗

Characterization of the Bacterioferritin/Bacterioferritin Associated Ferredoxin Protein-Protein Interaction in Solution and Determination of Binding Energy Hot Spots.Semantic proximity Read ↗

Dissociation between Iron and Heme Biosyntheses Is Largely Accountable for Respiration Defects of Shewanella oneidensis fur Mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.