Article
Identification and genetic analysis of wunen, a gene guiding Drosophila melanogaster germ cell migration.
Genetics - 1 Jul 1996
Zhang N, Zhang J, Cheng Y, Howard K
Abstract excerpt
We describe a novel genetic locus, wunen (wun), required for guidance of germ cell migration in early Drosophila development. Loss of wun function does not abolish movement but disrupts the orientation of the motion causing the germ cells to disperse even though their normal target, the somatic gonad, is well formed. We demonstrate that the product of this gene enables a signal to pass from the soma to the germ...
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