Article
Requirement for a noncoding RNA in Drosophila polar granules for germ cell establishment.
Science (New York, N.Y.) - 20 Dec 1996
Nakamura A, Amikura R, Mukai M, Kobayashi S, Lasko P F
Abstract excerpt
In Drosophila embryos, germ cell formation is induced by specialized cytoplasm at the posterior of the egg, the pole plasm. Pole plasm contains polar granules, organelles in which maternally produced molecules required for germ cell formation are assembled. An untranslatable RNA, called Polar granule component (Pgc), was identified and found to be localized in polar granules. Most pole cells in embryos produced...
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