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Article

Psychotic symptoms in Alzheimer's disease are not influenced by polymorphic variation at the dopamine receptor DRD3 gene.

Neuroscience letters - 16 Sept 2004

Craig David, Hart Dominic J, Carson Robyn, McIlroy Stephen P, Passmore A Peter

Abstract excerpt

It has been suggested that genetic influences unmasked during neurodevelopment to produce schizophrenia may appear throughout neurodegeneration to produce AD plus psychosis. Risk of schizophrenia and psychosis in Alzheimer's disease (AD) has been linked to polymorphic variation at the dopamine receptor DRD3 gene implying similar causative mechanisms. We tested this association in a large cohort of Alzheimer's...

Topics

Aged
Alleles
Alzheimer Disease
Cohort Studies
DNA
Delusions
Female
Genotype
Hallucinations
Humans
Logistic Models
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Psychotic Disorders

Receptors, Dopamine D2

Receptors, Dopamine D3

Source

Identifiers

PMID: 15342129
DOI: 10.1016/j.neulet.2004.06.052

Genes

DRD3
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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