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Article

No association between neuregulin 1 and psychotic symptoms in Alzheimer's disease patients.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Middle Fiona, Pritchard Antonia L, Handoko Herlina, Haque Sayeed, Holder Roger, Bentham Peter, Lendon Corinne L

Abstract excerpt

Alzheimer's disease (AD) patients commonly suffer from behavioral and psychological symptoms of dementia (BPSD). Variants within the neuregulin-1 (NRG1) gene have been investigated both in early onset psychiatric disorders, such as schizophrenia and recently in AD patients with psychosis. In this study, we analyzed NRG1 variants in AD patients with and without psychosis. Our large cohort of 399 probable AD...

Topics

Aged
Aged, 80 and over
Alzheimer Disease
Cohort Studies
Female
Gene Frequency
Genome-Wide Association Study
Genotype
Humans
Logistic Models
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Repeats

Neuregulin-1

Polymorphism, Single Nucleotide

Psychiatric Status Rating Scales

Psychotic Disorders

Source

Identifiers

PMID: 20182055
DOI: 10.3233/JAD-2010-1405

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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