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Article

Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation.

Journal of neurology, neurosurgery, and psychiatry - 1 Dec 2001

Holmes C, Smith H, Ganderton R, Arranz M, Collier D, Powell J, Lovestone S

Abstract excerpt

This study investigated possible associations between selected polymorphisms in the dopamine receptor genes DRD1 and DRD3 with the presence of psychotic phenomena or aggressive behaviour in a community based cohort of 134 patients with late onset Alzheimer's disease. An association was found between the presence of psychotic symptoms and aggressive behaviour and the DRD1 polymorphism and between the presence of...

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Source

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Identifiers

PMID: 11723200
DOI: 10.1136/jnnp.71.6.777
PMCID: PMC1737623

Genes

DRD1
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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