Article
Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease.
Archives of neurology - 1 Oct 1998
Sweet R A, Nimgaonkar V L, Kamboh M I, Lopez O L, Zhang F, DeKosky S T
Abstract excerpt
OBJECTIVE: To examine if selected polymorphisms in the dopamine receptor genes DRD1, DRD2, DRD3, and DRD4 are associated with the presence of psychosis or aggressive behavior in patients with Alzheimer disease (AD). DESIGN: A cohort of patients with AD were longitudinally evaluated for behavioral symptoms and classified with regard to the presence of psychotic symptoms and physical aggression. SETTING:...
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