Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease.

doi:10.1001/archneur.55.10.1335

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Article

Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease.

Archives of neurology - 1 Oct 1998

Sweet R A, Nimgaonkar V L, Kamboh M I, Lopez O L, Zhang F, DeKosky S T

Abstract excerpt

OBJECTIVE: To examine if selected polymorphisms in the dopamine receptor genes DRD1, DRD2, DRD3, and DRD4 are associated with the presence of psychosis or aggressive behavior in patients with Alzheimer disease (AD). DESIGN: A cohort of patients with AD were longitudinally evaluated for behavioral...

Topics

Aged
Aggression
Alzheimer Disease
Female
Genotype
Humans
Longitudinal Studies
Male
Polymorphism, Genetic
Psychiatric Status Rating Scales
Psychotic Disorders
Receptors, Dopamine

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