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Article

Identification of MMP-15 as an anti-apoptotic factor in cancer cells.

The Journal of biological chemistry - 7 Oct 2005

Abraham Reimar, Schäfer Juliane, Rothe Mike, Bange Johannes, Knyazev Pjotr, Ullrich Axel

Abstract excerpt

We have performed an in vitro selection for an anti-apoptotic phenotype that resembles the selection process that pre-malignant cells undergo in the initial phase of carcinogenesis in vivo. Using the cervical carcinoma cell line HeLa S3 as a model system, the selection procedure yielded cell clones that displayed increased resistance to apoptosis induced by Fas, tumor necrosis factor-related apoptosis-inducing...

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Source

Identifiers

PMID: 16093241
DOI: 10.1074/jbc.M508155200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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