Article
Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma.
Molecular cancer research : MCR - 1 Mar 2008
Zhong Julia L, Poghosyan Zaruhi, Pennington Caroline J, Scott Xanthe, Handsley Madeleine M, Warn Alba, Gavrilovic Jelena, Honert Katja, Krüger Achim, Span Paul N, Sweep Fred C G J, Edwards Dylan R
Abstract excerpt
Adamalysins [a disintegrin and metalloproteinase (ADAM)] are a family of cell surface transmembrane proteins that have broad biological functions encompassing proteolysis, adhesion, and cell signal regulation. We previously showed that the cytoplasmic domain of ADAM-15 interacts with Src family p...
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