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Article

Ultrastructural organization of ex vivo amyloid fibrils formed by the apolipoprotein A-I Leu174Ser variant: an atomic force microscopy study.

Biochimica et biophysica acta - 6 Sept 2004

Relini Annalisa, Rolandi Ranieri, Bolognesi Martino, Aboudan Manuela, Merlini Giampaolo, Bellotti Vittorio, Gliozzi Alessandra

Abstract excerpt

Atomic force microscopy was employed to study ex vivo amyloid material isolated from the transplanted hearts of two patients affected by systemic amyloidosis caused by the Leu174Ser apolipoprotein A-I variant. The purified material consists of fibrils and globular aggregates. For both patients the same morphological patterns are observed; in addition, fibril diameters obtained for the two patients turn out to be...

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PMID: 15337168
DOI: 10.1016/j.bbadis.2004.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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