Article
Prevalence of the K469E polymorphism of intercellular adhesion molecule 1 gene in Italian patients with inflammatory bowel disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Aug 2004
Papa A, Pola R, Flex A, Danese S, Armuzzi A, Gaetani E, Guidi L, De Vitis I, Urgesi R, Grillo A, Serricchio M, Proia A S, Fedeli G, Gasbarrini G, Pola P, Gasbarrini A
Abstract excerpt
BACKGROUND: Intercellular adhesion molecule 1 plays an important role in the recruitment of leucocytes at sites of inflammation and is up-regulated in intestinal mucosa of inflammatory bowel disease. Intercellular adhesion molecule 1 gene lies on chromosome 19p13, implicated in determining susceptibility to inflammatory bowel disease. Recently, the polymorphism K469E of intercellular adhesion molecule 1 gene has...
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