Article
Polymorphism in ICAM-1, PECAM-1, E-selectin, and L-selectin genes in Tunisian patients with inflammatory bowel disease.
European journal of gastroenterology & hepatology - 1 Feb 2009
Khazen Dorra, Jendoubi-Ayed Saloua, Aleya Walid Ben, Sfar Imen, Mouelhi Leila, Matri Samira, Najjar Tawfik, Filali Azza, Gorgi Yousr, Abdallah Taieb Ben, Ayed Khaled
Abstract excerpt
BACKGROUND: Ulcerative colitis (UC) and Crohn's disease (CD) are chronic intestinal disorders characterized by immune dysregulation and leukocytes recruitment into gastrointestinal tract. Cell adhesion molecules (CAM) mediate the extravasation of leukocytes and their accumulation in inflamed inte...
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