Article
Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells.
Genes, chromosomes & cancer - 1 Nov 2004
MacGrogan Donal, Kalakonda Nagesh, Alvarez Sara, Scandura Joseph M, Boccuni Piernicola, Johansson Bertil, Nimer Stephen D
Abstract excerpt
The human L3MBTL gene is located in 20q12, a region that is commonly deleted in myeloproliferative disorders (MPD), myelodysplastic syndromes (MDS), and acute myeloid leukemia (AML). L3MBTL is highly homologous to the D-lethal(3) malignant brain tumor [D-l(3)mbt] gene, which is a putative tumor-suppressor gene (TSG) identified in Drosophila and which is closely related to the Drosophila sex combs on midleg (SCM)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
