Article
Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies.
Proceedings of the National Academy of Sciences of the United States of America - 11 May 2004
Li Juan, Bench Anthony J, Vassiliou George S, Fourouclas Nasios, Ferguson-Smith Anne C, Green Anthony R
Abstract excerpt
L3MBTL encodes a member of the Polycomb family of proteins, which, together with Trithorax group proteins, is responsible for the coordinated regulation of patterns of gene activity. Members of the Polycomb family also regulate self renewal of normal and malignant hematopoietic stem cells. L3MBTL lies in a region of chromosome 20, deletion of which is associated with myeloid malignancies and represents a good...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
