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Article

MLL3 , a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia

1 Feb 2002

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11891048
DOI: 10.1016/s0378-1119(02)00392-x

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 11 closest

MLL3 , a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemiaPMID 11891048Read ↗

MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid LeukemiaSemantic proximity Read ↗

Insights from clinical studies into the role of the MLL gene in infant and childhood leukemiaSemantic proximity Read ↗

Recurrent involvement of the MLL gene in adult T-lineage acute lymphoblastic leukemiaSemantic proximity Read ↗

MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell linesSemantic proximity Read ↗

THE CRITICAL ROLE OF CHROMOSOME TRANSLOCATIONS IN HUMAN LEUKEMIASSemantic proximity Read ↗

MLL: how complex does it get?Semantic proximity Read ↗

Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells.Semantic proximity Read ↗

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.Semantic proximity Read ↗

Localization of the Human Stat6 Gene to Chromosome 12q13.3–q14.1, a Region Implicated in Multiple Solid TumorsSemantic proximity Read ↗

Truncation of the Mll gene in exon 5 by gene targeting leads to early preimplantation lethality of homozygous embryos.Semantic proximity Read ↗

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignanciesSemantic proximity Read ↗

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