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Article

YMDD mutants in patients with chronic hepatitis B before treatment are not selected by lamivudine.

Journal of medical virology - 1 Oct 2004

Matsuda Marie, Suzuki Fumitaka, Suzuki Yoshiyuki, Tsubota Akihito, Akuta Norio, Hosaka Tetsuya, Someya Takashi, Kobayashi Masahiro, Saitoh Satoshi, Arase Yasuji, Satoh Junko, Kobayashi Mariko, Ikeda Kenji, Miyakawa Yuzo, Kumada Hiromitsu

Abstract excerpt

Hepatitis B virus (HBV) mutants with mutations in the YMDD motif of viral DNA polymerase/reverse transcriptase are described in patients infected with HBV who have not received lamivudine therapy, but their pathogenetic potential is not clear. These mutants were detected by the polymerase chain reaction with peptide nucleic acid clamping in pretreatment sera from two patients who later received lamivudine. One...

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Identifiers

PMID: 15332287
DOI: 10.1002/jmv.20185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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YMDD mutants in patients with chronic hepatitis B before treatment are not selected by lamivudine.PMID 15332287Read ↗

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