Article
Adherence of Candida albicans to silicone induces immediate enhanced tolerance to fluconazole.
Antimicrobial agents and chemotherapy - 1 Sept 2004
Mateus Carolina, Crow Sidney A, Ahearn Donald G
Abstract excerpt
Wild-type and efflux pump-deficient cells of Candida albicans adhering to silicone were compared with planktonic cells by flow cytometry for their relative resistance to fluconazole (FCZ). Flow cytometry data on cells carrying a fusion of green fluorescent protein to efflux pump promoters confirmed that enhanced tolerance of attached cells to FCZ was due in part to increased expression of CaMDR1 and CDR1...
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