Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms.

The Journal of antimicrobial chemotherapy - 1 Jun 2002

Ramage Gordon, Bachmann Stefano, Patterson Thomas F, Wickes Brian L, López-Ribot José L

Abstract excerpt

A main characteristic associated with microbial biofilms is their increased resistance to antimicrobial chemotherapies. However, at present very little is known about the phenotypic changes that occur during the transition from the planktonic to the biofilm mode of growth. Candida albicans biofilms displayed an organized three-dimensional structure, and consisted of a dense network of yeasts and filamentous cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B
Share to Biofilms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biological Transport, Active

Share to Candida albicans

Share to Drug Resistance, Fungal

Share to Fluconazole

Share to Fungal Proteins

Share to Mutation

Source

Identifiers

PMID: 12039889
DOI: 10.1093/jac/dkf049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms.PMID 12039889Read ↗

Mechanism of fluconazole resistance in Candida albicans biofilms: phase-specific role of efflux pumps and membrane sterols.Semantic proximity Read ↗

Expression of fluconazole resistance-associated genes in biofilm from 23 clinical isolates of Candida albicansSemantic proximity Read ↗

Linking quorum sensing regulation and biofilm formation by Candida albicans.Semantic proximity Read ↗

Doxorubicin induces drug efflux pumps inCandida albicansSemantic proximity Read ↗

Difference in virulence between fluconazole-susceptible and fluconazole-resistant Candida albicans in a mouse model.Semantic proximity Read ↗

[Investigation of mutations in transcription factors of efflux pump genes in fluconazole-resistant Candida albicans strains overexpressing the efflux pumps].Semantic proximity Read ↗

Adherence of Candida albicans to silicone induces immediate enhanced tolerance to fluconazole.Semantic proximity Read ↗

Overexpression of CDR1 and CDR2 genes plays an important role in fluconazole resistance in Candida albicans with G487T and T916C mutations.Semantic proximity Read ↗

The evaluation of the overexpression of theERG‐11,MDR‐1,CDR‐1, andCDR‐2genes in fluconazole‐resistantCandida albicansisolated from Ahvazian cancer patients with oral candidiasisSemantic proximity Read ↗

Transcriptional Analyses of Antifungal Drug Resistance in Candida albicansSemantic proximity Read ↗

Activation of the multiple drug resistance gene MDR1 in fluconazole-resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor.Semantic proximity Read ↗

The calcineruin inhibitor cyclosporine a synergistically enhances the susceptibility of Candida albicans biofilms to fluconazole by multiple mechanismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.