Article
Functional domains in the feline immunodeficiency virus nucleocapsid protein.
Virology - 15 Sept 2004
Manrique Mariana L, Rauddi María L, González Silvia A, Affranchino José L
Abstract excerpt
Retroviral nucleocapsid (NC) proteins are small Gag-derived products containing one or two zinc finger motifs that mediate genomic RNA packaging into virions. In this study, we addressed the role of the feline immunodeficiency virus (FIV) NC protein in the late stages of virus replication by analyzing the assembly phenotype of FIV NC mutant viruses and the RNA binding activity of a panel of recombinant FIV NC...
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