Viral RNA annealing activities of the nucleocapsid protein of Moloney murine leukemia virus are zinc independent.

doi:10.1093/nar/19.13.3533

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Article

Viral RNA annealing activities of the nucleocapsid protein of Moloney murine leukemia virus are zinc independent.

Nucleic acids research - 11 Jul 1991

Prats A C, Housset V, de Billy G, Cornille F, Prats H, Roques B, Darlix J L

Abstract excerpt

The zinc fingers of retroviral gag nucleocapsid proteins (NC) are required for the specific packaging of the dimeric RNA genome into virions. In vitro, NC proteins activate both dimerization of viral RNA and annealing of the replication primer tRNA onto viral RNA, two reactions necessary for the production of infectious virions. In this study the role of the zinc finger of Moloney murine leukemia virus (MoMuLV)...

Topics

Alkylation
Amino Acid Sequence
Base Sequence
Capsid
Cloning, Molecular
Cysteine
Escherichia coli
Kinetics
Lysine
Molecular Sequence Data
Moloney murine leukemia virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Plasmids

RNA, Transfer, Pro

RNA, Viral

Viral Core Proteins

Zinc

Zinc Fingers

Source

Open in PubMed Open full text

Identifiers

PMID: 1906602
DOI: 10.1093/nar/19.13.3533
PMCID: PMC328376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1906602-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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