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Article

Mutation of TCF1 encoding hepatocyte nuclear factor 1alpha in gynecological cancer.

Oncogene - 30 Sept 2004

Rebouissou Sandra, Rosty Christophe, Lecuru Fabrice, Boisselier Sophie, Bui Hung, Le Frere-Belfa Marie-Aude, Sastre Xavier, Laurent-Puig Pierre, Zucman-Rossi Jessica

Abstract excerpt

TCF1: (transcription factor 1) encoding hepatocyte nuclear factor 1alpha (HNF1alpha) is mutated in 50% of liver cell adenomas, a benign tumor closely associated with oral contraceptive use. These genetic alterations inactivate both alleles, leading to the absence of wild-type HNF1alpha expression...

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Identifiers

PMID: 15326484
DOI: 10.1038/sj.onc.1207989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15326484-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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