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Article

Hepatocellular adenoma displaying a HNF1alpha inactivation in a patient with familial adenomatous polyposis coli.

Journal of hepatology - 1 Dec 2006

Jeannot Emmanuelle, Wendum Dominique, Paye François, Mourra Najat, de Toma Claudia, Fléjou Jean-François, Zucman-Rossi Jessica

Abstract excerpt

Patients with familial adenomatous polyposis coli (FAP) may rarely develop hepatocellular adenoma. Here we report the case of a 37-year-old FAP woman presenting a hepatocellular adenoma after oestroprogestative oral contraception use. In this steatotic adenoma, we identified an inactivating biallelic mutation of HNF1alpha. In addition to the known germline APC mutation Q1062fs, we did not find an inactivation of...

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Share to Adenomatous Polyposis Coli
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Gene Silencing

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Source

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Identifiers

PMID: 17049664
DOI: 10.1016/j.jhep.2006.06.020
PMCID: PMC2121664

Genes

FAP
APC
GLUL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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