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Article

Visual recovery in patients with Leber's hereditary optic neuropathy and the 11778 mutation.

Journal of clinical neuro-ophthalmology - 1 Mar 1992

Stone E M, Newman N J, Miller N R, Johns D R, Lott M T, Wallace D C

Abstract excerpt

Five patients with Leber's hereditary optic neuropathy (LHON) and the 11778 mitochondrial mutation spontaneously recovered 20/40 or better visual acuity in at least one eye after months to years of legal blindness. The patients ranged in age from 9 to 45 years, and the duration of visual loss before recovery ranged from several months to 5.9 years. These patients constitute only about 4% of the 136 affected LHON...

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Source

Identifiers

PMID: 1532593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The clinical characteristics of pedigrees of Leber's hereditary optic neuropathy with the 11778 mutation.Semantic proximity Read ↗

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