Visual recovery in patients with Leber's hereditary optic neuropathy and the 11778 mutation.

Article

Visual recovery in patients with Leber's hereditary optic neuropathy and the 11778 mutation.

Journal of clinical neuro-ophthalmology - 1 Mar 1992

Stone E M, Newman N J, Miller N R, Johns D R, Lott M T, Wallace D C

Abstract excerpt

Five patients with Leber's hereditary optic neuropathy (LHON) and the 11778 mitochondrial mutation spontaneously recovered 20/40 or better visual acuity in at least one eye after months to years of legal blindness. The patients ranged in age from 9 to 45 years, and the duration of visual loss bef...

Topics

Adolescent
Child
DNA, Mitochondrial
Female
Humans
Male
Middle Aged
Mutation
Optic Atrophies, Hereditary
Remission, Spontaneous
Vision Disorders
Visual Acuity
Visual Fields

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.