Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retinal ganglion cell dysfunction in asymptomatic G11778A: Leber hereditary optic neuropathy.

Investigative ophthalmology & visual science - 10 Feb 2014

Guy John, Feuer William J, Porciatti Vittorio, Schiffman Joyce, Abukhalil Fawzi, Vandenbroucke Ruth, Rosa Potyra R, Lam Byron L

Abstract excerpt

PURPOSE: To report the serial evaluation of asymptomatic eyes of subjects with mutated G11778A mitochondrial DNA. METHODS: Forty-five asymptomatic G11778A Leber hereditary optic neuropathy (LHON) carriers and two patients with the mutation who developed unilateral visual loss underwent testing that included visual acuity, automated visual field, pattern electroretinogram (PERG), and spectral-domain optical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electroretinography
Share to Optic Atrophy, Hereditary, Leber

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Retinal Diseases

Share to Retinal Ganglion Cells

Share to Tomography, Optical Coherence

Share to Vision Disorders

Share to Visual Acuity

Share to Visual Fields

Source

Open in PubMed Open full text

Identifiers

PMID: 24398093
DOI: 10.1167/iovs.13-13365
PMCID: PMC3920864

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retinal ganglion cell dysfunction in asymptomatic G11778A: Leber hereditary optic neuropathy.PMID 24398093Read ↗

Retinal Sublayer Thickness Analysis of The Macula of Symptomatic and Asymptomatic Carriers of G11778A Mutations with Leber's Hereditary Optic NeuropathySemantic proximity Read ↗

Optic Nerve Structural and Functional Changes in LHON-Affected and Asymptomatic Maternal Relatives: Association with H and HV Mitochondrial Haplogroups.Semantic proximity Read ↗

PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation.Semantic proximity Read ↗

THREE-DIMENSIONAL CHARACTERISTICS OF FOUR MACULAR INTRARETINAL LAYER THICKNESSES IN SYMPTOMATIC AND ASYMPTOMATIC CARRIERS OF G11778A MUTATION WITH LEBER'S HEREDITARY OPTIC NEUROPATHY.Semantic proximity Read ↗

[Measurement of retinal nerve fiber layer thickness in Leber hereditary optic neuropathy by optical coherence tomography].Semantic proximity Read ↗

Retinal nerve fiber layer thickness variability in Leber hereditary optic neuropathy carriers.Semantic proximity Read ↗

Leber hereditary optic neuropathy: clinical and molecular genetic findings.Semantic proximity Read ↗

Colour vision defects in asymptomatic carriers of the Leber's hereditary optic neuropathy (LHON) mtDNA 11778 mutation from a large Brazilian LHON pedigree: a case-control study.Semantic proximity Read ↗

Leber hereditary optic neuropathy: mitochondrial mutations and degeneration of the optic nerve.Semantic proximity Read ↗

Atypical Leber's hereditary optic neuropathy with molecular confirmation.Semantic proximity Read ↗

Clinical features of Leber's hereditary optic neuropathy with the 11778 mitochondrial DNA mutation in Taiwanese patients.Semantic proximity Read ↗

Juvenile open-angle Glaucoma associated with Leber’s hereditary optic neuropathy: a case report and literature reviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.